Eupatorin
APC-868
Eupatorin
Cat. No.
APC-868
CAS No.
855-96-9
MF
C18H16O7
MW
344.319
Eupatorin is a naturally occurring flavonoid that can arrest the G2-M cell cycle, activate multiple caspases, the release of cytochrome C, the cleavage of poly (ADP-ribose) polymerase, and induce apoptotic cell death.
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Technical Data
Description
Storage and Shipping
References
Product Name
CAS No.
855-96-9
MF
C18H16O7
MW
344.319
Specification
95%-98%
Research Area
Anti-inflammatory, anti-tumor and antioxidant
Description
Eupatorin is a naturally occurring flavonoid that can arrest the G2-M cell cycle, activate multiple caspases, the release of cytochrome C, the cleavage of poly (ADP-ribose) polymerase, and induce apoptotic cell death. Packing: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g Availability: In stock
Documents
Certificate of Analysis (COA), Specification Sheet, HPLC, 1HNMR, 13CNMR, IR, MS, Safety Data Sheet (SDS/MSDS) etc.
Storage and Shipping
Store under frozen or refrigerated conditions, keep away from strong light and heat.
References
[1]. Dolečková I, et al. Antiproliferative and antiangiogenic effects of flavone eupatorin, an active constituent of chloroform extract of Orthosiphon stamineus, leaves[J]. Fitoterapia, 2012, 83(6):12000-12007.
[2]. Estévez S, et al. Eupatorin-induced cell death in human leukemia cells is dependent on caspases and activates the mitogen-activated protein kinase pathway.[J]. Plos One, 2014, 9(11):e112536.
[3]. Laavola M, et al. Flavonoids eupatorin and sinensetin present in Orthosiphon stamineus leaves inhibit inflammatory gene expression and STAT1 activation[J]. Planta Medica, 2012, 78(08):779-786.
[4]. Androutsopoulos V, et al. Antiproliferative and cytostatic effects of the natural product eupatorin on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism[J]. Breast Cancer Research,10,3(2008-05-02), 2008, 10(3):R39.
[2]. Estévez S, et al. Eupatorin-induced cell death in human leukemia cells is dependent on caspases and activates the mitogen-activated protein kinase pathway.[J]. Plos One, 2014, 9(11):e112536.
[3]. Laavola M, et al. Flavonoids eupatorin and sinensetin present in Orthosiphon stamineus leaves inhibit inflammatory gene expression and STAT1 activation[J]. Planta Medica, 2012, 78(08):779-786.
[4]. Androutsopoulos V, et al. Antiproliferative and cytostatic effects of the natural product eupatorin on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism[J]. Breast Cancer Research,10,3(2008-05-02), 2008, 10(3):R39.
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
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